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. Author manuscript; available in PMC: 2016 Jul 1.
Published in final edited form as: DNA Repair (Amst). 2015 Apr 25;31:41–51. doi: 10.1016/j.dnarep.2015.04.006

Table 2.

Contributions of selectivity, proofreading and MMR to replication fidelity.

Leading strand
Lagging strand
Base selectivity Proofreading MMR Base selectivity Proofreading MMR
12000000 160 65 2000000 1000 250
Transitions 21000000 73 130 1000000 1500 330
 T-dG 55000000 340 130 490000 5800 240
 A-dC 83000000 34 44 25000000 750 >=120
 G-dT 32000000 400 120 670000 990 550
 C-dA 11000000 62 150 20000000 630 48
Transversions 14000000 300 54 17000000 250 77
 T-dT 30000000 910 5.8 47000000 750 58
 A-dA 63000000 570 41 36000000 750 35
 A-dG >=260000000 =<110 a >=69000000 =<130 a
 T-dC 77000000 110 22 11000000 2800 58
 G-dA 230000000 7.1 66 81000000 38 58
 C-dT 4300000 700 490 6600000 250 180
 G-dG >=120000000 =<340 =<66 92000000 130 58
 C-dC >=200000000 =<57 =<66 >=56000000 =<750 b
a

Too few events detected to quantify a contribution.