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. Author manuscript; available in PMC: 2016 May 21.
Published in final edited form as: Cell. 2015 May 7;161(5):1112–1123. doi: 10.1016/j.cell.2015.04.003

Figure 1. Crystal structure of the Homo sapiens TTLL7 core.

Figure 1

(A) Ribbon representation of the TTLL7 core bound to ADP. Nucleotide shown as a stick model. Spheres represent disordered polypeptide chain regions. c-MTBD residues, orange spheres.

(B,C) Superposition of TTLL7 and TTL (PDB ID 3TII; grey) crystal structures; (B), nucleotide binding view, (C), side-view, 90° rotated from (B).

(D, E) Close-up views showing residues important for helix α9 packing with the TTL-homologous core. See also Table S1 and Figure S1.