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Effects of heat stress on IL-1β and TNF-α production in the mouse hippocampus. Male imprinting control region (ICR) mice were exposed to high temperature for 7, 14, or 42 days. Expression of IL-1β (a) and TNF-α (b) was assessed using a sandwich enzyme-linked immunosorbent assay (ELISA). Values are expressed as means ± S.E.M. *p < 0.05, **p < 0.01, and ***p < 0.001 as compared with the control group
