Table 1. Comparison of epidemiological risk-factors among infants with and without C+ve infections in the VLBW cohort.
Data is represented as mean ± SD or as percentages. Comparisons between gestational age and birth-weight were done using non-parametric tests. Other comparisons were done using Chi-Square or Fisher’s exact tests. Chorioamnionitis was diagnosed by the presence of maternal fever >38°C plus one additional criteria (uterine tenderness, malodorous vaginal discharge, maternal leukocytes >15,000 cells/mm3 or fetal heart-rate of >160/min).
| Clinical Variable | No infection (n=318) Median (25%, 75%) or % |
Infection present (n=90) Median (25%, 75%) or % |
|---|---|---|
|
| ||
| Gestational age (weeks) | 29 (27, 30) | 26 (24, 27) * |
|
| ||
| Birth-weight (grams) | 1130 (869, 1311) | 755 (630, 982)* |
|
| ||
| Race - Caucasians | 68.9 | 73 |
| African American | 28.3 | 25.5 |
| Others | 2.8 | 2.2 |
|
| ||
| Antenatal steroids use | 84 | 91 |
|
| ||
| Male sex | 50.3 | 57.8 |
|
| ||
| Clinical chorioamnionitis | 10.4 | 17.8 ¶ |
|
| ||
| Prenatal Care | 96.3 | 95.6 |
|
| ||
| Inborn | 90 | 86.7 |
|
| ||
| 5-min Apgar score | 8 (6, 9) | 7 (6, 8) # |
|
| ||
| CVL days (Mean ± SD) | 14.6 ± 16 | 35.4 ± 26 * |
*
P<0.001,
¶
P=0.06,
#
P=0.004