Table 2.

Univariate and multivariate analysis of prognostic factors in 112 CRC patients for overall survival

	Univariate analysis			Multivariate analysis
	HR	p value	95 % CI	HR	p value	95 % CI
Rab27A protein expression
High versus Low or no	0.33	0.001*	0.181–0.616	0.36	0.012*	0.159–0.794
Gender
Male versus Female	1.43	0.277	0.750–2.726
Age (years)
≥60 versus <60	1.16	0.642	0.618–2.184
Tumor size (cm)
≥5 versus <5	1.21	0.537	0.659–2.224
Tumor location
Colon versus Rectum versus Ileocecal junction	1.49	0.131	0.888–2.495
Histological type
Adenocarcinoma versus Non-adenocarcinoma	2.40	0.227	0.581–9.903
Tumor differentiation
Well-Moderately versus Poorly	0.23	0.001*	0.117–0.449	0.30	0.004*	0.134–0.689
Serum CEA level (ng/ml)
≥15 versus <15	2.83	0.006*	1.356–5.894	1.64	0.228	0.735–3.639
T (Primary tumor)
T1 versus T2 versus T3	0.31	0.004*	0.140–0.692	0.70	0.566	0.201–2.406
N (Lymph node metastasis)
Positive versus Negative	1.41	0.257	0.780–2.533
M (Distant metastasis)
Positive versus Negative	4.35	0.005*	1.542–12.171	2.53	0.281	0.467–13.772
TNM stage
Stage I versus Stage II versus Stage III versus Stage IV	0.58	0.003*	0.403–0.829	0.68	0.281	0.333–1.375

*p < 0.05