Table 1.
Clinical trial sites among industry-sponsored trials registered in ClinicalTrials.gov
| Major geographic groups and country regions | Total number of trials a (N = 22,511) | Trials conducted exclusively outside high-income regions a, N (%) (N = 2,045) | Total number of study sites | Trials/10 million population a |
|---|---|---|---|---|
| America | 2,245 | 445 (19.8) | 22,296 | 36.7 |
| Andean Latin America | 444 | 22 (5.0) | 1,507 | 78.2 |
| Caribbean | 138 | 28 (20.3) | 614 | 35.4 |
| Central Latin America | 1,321 | 143 (10.8) | 6,902 | 53.7 |
| Southern Latin America | 1,139 | 69 (6.1) | 7,239 | 182.3 |
| Tropical Latin America | 1,067 | 231 (21.6) | 6,034 | 51.5 |
| Middle East/Africa | 1,447 | 203 (14.1) | 8,294 | 10.1 |
| Eastern Sub-Saharan Africa | 55 | 43 (78.2) | 197 | 1.4 |
| North Africa and Middle East | 727 | 85 (11.7) | 2,875 | 14.6 |
| Central sub-Saharan Africa | 57 | 11 (19.3) | 41 | 5.7 |
| Southern sub-Saharan Africa | 911 | 60 (6.4) | 4,903 | 121.8 |
| Western sub-Saharan Africa | 97 | 39 (40.2) | 278 | 2.6 |
| Asia | 2,845 | 1198 (42.1) | 23,448 | 7.6 |
| Central Asia | 107 | 19 (17.8) | 291 | 12.4 |
| East Asia | 1,742 | 728 (41.8) | 11,502 | 12.6 |
| Oceania | 39 | 2 (5.1) | 16 | 40.6 |
| South Asia | 1,157 | 324 (20.0) | 7,234 | 7.1 |
| Southeast Asia | 867 | 161 (18.6) | 4,405 | 13.7 |
| Europe (non-Western) | 3,536 | 308 (8.7) | 58,960 | 109.0 |
| Eastern Europe | 2,075 | 159 (7.7) | 20,685 | 99.6 |
| Central Europe | 3,127 | 200 (6.4) | 38,275 | 269.0 |
| More-developed | 20,466 | – | 378,331 | 207.5 |
| Australasia | 1,775 | – | 9,718 | 643.1 |
| Western Europe | 8,591 | – | 123,019 | 202.5 |
| High-income Asia Pacific | 2,859 | – | 23,441 | 155.9 |
| High-income North America | 12,992 | – | 222,153 | 369.8 |
a Trials with study sites in more than one country region were included separately in each region
b Population data from World Bank, 2013. Available at data.worldbank.org