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. Author manuscript; available in PMC: 2015 Jun 14.
Published in final edited form as: Pharmacol Ther. 2008 Oct 31;121(2):132–146. doi: 10.1016/j.pharmthera.2008.09.008

Table 1.

Prolyl Endopeptidase Substrates and Inhibitors

Compound Structure/Sequence Function Reference
Oxytocin graphic file with name nihms99491t1.jpg Hormone (Walter, Shlank, Glass, Schwartz, & Kerenyi, 1971)
Z-Gly-Pro-Ala-OH graphic file with name nihms99491t2.jpg POP Activity Assay (Garcia- Horsman, Mannisto, & Venalainen, 2007)
Z-Gly-Pro-pNA graphic file with name nihms99491t3.jpg POP Activity Assay (Zolfaghari et al., 1986)
Suc-Ala-Pro-pNA graphic file with name nihms99491t4.jpg POP Activity Assay (Garcia- Horsman, Mannisto, & Venalainen, 2007)
ZPP graphic file with name nihms99491t5.jpg Inhibitor (Bakker, Jung, Spencer, Vinick, & Faraci, 1990)
JTP-4819 graphic file with name nihms99491t6.jpg Inhibitor (Toide, Okamiya, Iwamoto, & Kato, 1995)
ONO-1603 graphic file with name nihms99491t7.jpg Inhibitor (Katsube, Sunaga, Chuang, & Ishitani, 1996)
SUAM-1221 graphic file with name nihms99491t8.jpg Inhibitor (Atack, Suman- Chauhan, Dawson, & Kulagowski, 1991)