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. 2015 Jun;4(3):211–215. doi: 10.3978/j.issn.2304-3881.2015.01.10

Table 1. Histologic effects of thermal ablation modalities (radio-frequency, microwave ablation, and cryo-ablation) and irreversible electroporation.

Effect Thermal ablation Irreversible electroporation
Act of damage Entire cell Only cell membrane
Protein denaturation Typical Not present
Blood flow Effects efficacy ablation No effect
Connective tissue Damaged Spared
Region of damage Gradual change Better defined
IHC effects Present Not present

IHC, immuno-histochemistry.