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. 2015 Jun 10;10(6):e0129693. doi: 10.1371/journal.pone.0129693

Fig 5. PI3-kinase-dependent propofol treatment abolishes cell apoptosis in primary neutrophils and ATRA-differentiated granulocytic HL60 cells.

Fig 5

(A) Isolated human primary neutrophils and (B) ATRA (1 μM)-differentiated granulocytic HL60 cells were treated with propofol with or without LY294002 treatment for the indicated time points. PI and PI/Annexin V-FITC staining followed by flow cytometric analysis determined the apoptosis levels. The percentages of apoptotic cells (sub-G1 and Annexin V+/PI-) are shown as the means ± SD of three individual experiments. **P < 0.01 and ***P < 0.001 compared with untreated at 0 h. #P < 0.05 and ##P < 0.01 compared with untreated at each time points. †P < 0.05 and ††P < 0.01 compared with propofol. ns, not significant compared with propofol plus LY294002.