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. Author manuscript; available in PMC: 2015 Jun 18.
Published in final edited form as: Nature. 2014 Oct 12;516(7531):432–435. doi: 10.1038/nature13833

Extended Data Figure 3. Contact probability as a function of genomic distance in wild type and rad21-K1.

Extended Data Figure 3

Global decay of intra-arm contact probability as a function of genomic distance plotted for rad21-K1 (blue) and wild type (grey line). Average inter-chromosomal interactions (flat lines) are markedly increased (~twofold) in rad21-K1 compared to wild type. Short-range contact probability decays rapidly in rad21-K1, and no longer decreases more rapidly after 100kb, probably reflecting the loss of globules in rad21-K1. The black and grey dashed lines represent the slope for fractal globules (-1) and polymers in a melt (-3/2), respectively.