Table 2.
Univariate and multivariate analyses for recurrence-free survival (Cox proportional hazard model).
| Variable | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P value | HR | 95% CI | P value | |
| Age (≥65 versus <65 year old) | 1.116 | 0.652–1.908 | 0.689 | |||
| Sex (male versus female) | 0.844 | 0.495–1.441 | 0.535 | |||
| Tumor site | ||||||
| Colon versus rectum | 1.075 | 0.635–1.821 | 0.788 | |||
| Histology | ||||||
| Poor versus well/moderate | 1.548 | 0.832–2.881 | 0.168 | |||
| Lymph node metastasis | ||||||
| n ≥ 4 versus n < 4 | 2.160 | 1.230–3.793 | 0.007 | 0.832 | 0.409–1.693 | 0.612 |
| TNM stage | ||||||
| IIIC versus IIIA + IIIB | 4.001 | 2.281–7.017 | <0.001 | 5.057 | 2.478–10.323 | <0.001 |
| PPP1R12A (low versus high) | 2.186 | 1.293–3.696 | 0.003 | 2.596 | 1.500–4.490 | 0.001 |
Bold items highlight P < 0.05, HR: hazard ratio, CI: confidence interval; TNM: tumor node metastasis.