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. Author manuscript; available in PMC: 2015 Jun 14.
Published in final edited form as: Circ Res. 2013 Mar 26;112(10):1310–1322. doi: 10.1161/CIRCRESAHA.112.300227

Figure 8. Comparison of Ito properties obtained from different subunit-combinations in heterologous expression system.

Figure 8

Examples of currents recorded in Chinese hamster ovary cells transiently transfected with Kv4.3 (A), Kv4.3+K+-channel interacting protein type-2 (KChIP2; B), Kv4.3+KChIP2+DPP6 (C), Kv4.3+neuronal calcium sensor-1 (NCS-1; D), Kv4.3+NCS-1+DPP6 (E), or Kv4.3+DPP6 (F). Currents were recorded during 250-millisecond depolarizations at 0.1 Hz. G, Mean±SEM current densities at 30 mV. *P<0.05, **P<0.01, ***P<0.001 vs Kv4.3 only. H, Mean±SEM inactivation time constants at 40 mV. *P<0.05, **P<0.01, ***P<0.001 vs Kv4.3 only. I, Representative fts from 2 experiments. J, Mean±SEM recovery time constants obtained as illustrated in Online Figure VIIIB. *P<0.05, vs Kv4.3+KChIP2.