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(A,B) Change in recurrent (A) and non-stable (B) POUS-DNA contacts when pulling the POUHD. (C-F) Change in recurrent (C,E) and non-stable (D,F) contacts between the globular region (C,D) and the N-terminal tail (E,F) of the POUHD when pulling the POUS. The fraction of recurrent contacts defined as in Fig 4. See also S5 Fig.
