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. Author manuscript; available in PMC: 2016 Jul 1.
Published in final edited form as: Hypertension. 2015 May 4;66(1):117–125. doi: 10.1161/HYPERTENSIONAHA.115.05484

Figure 3. Complement activation in the kidneys of sFlt-1–injected mice as a model of preeclampsia.

Figure 3

Representative images of C4 deposits in a glomerulus from an sFlt-1–injected (A) and a control-treated (B) mouse. The average (±SD) percentage of C4-positive glomeruli (C) is significantly higher in the kidneys of sFlt-1–injected mice (N=6 mice) than control-treated mice (N=5 mice). sFlt-1–injected mice had significantly higher levels of activated C3 fragments in the serum compared to control-treated mice (D). *p<0.05, **p<0.01. AU = arbitrary units.