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. Author manuscript; available in PMC: 2016 Jul 1.
Published in final edited form as: Hypertension. 2015 Apr 27;66(1):211–220. doi: 10.1161/HYPERTENSIONAHA.115.05332

Figure 4. Role of Smooth Muscle PPARγ in S-P467L Mice.

Figure 4

A) S-P467L mice and their non-transgenic littermates had a significant increase in systolic blood pressure seven days after elastase injection that was sustained until 21 days, but was not significantly different between cohorts at any time point after injection. The incidence of aneurysms (B) was significantly increased (p<0.05), and subarachnoid hemorrhage (C) showed a strong trend toward increase (p=0.05) in S-P467L mice versus their non-transgenic littermates. D) Kaplan Meier analysis demonstrated a significant decrease in survival in the S-P467L cohort (Log rank p<0.05). S-P467L, n=16; NT, n=10 for A-D. (* is P value <0.05; ** is P=0.051).