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. Author manuscript; available in PMC: 2016 Jan 1.
Published in final edited form as: Ann Rheum Dis. 2014 Dec 12;75(1):183–189. doi: 10.1136/annrheumdis-2014-206133

Table 3.

Arthritis-related diseases in first-degree relatives associated to proband’s rheumatoid arthritis (RA), by proband’s serostatus

Disease in relative Seropositive RA, OR (95% CI) Seronegative RA, OR (95% CI) Ratio of ORs (95% CI)
Seropositive RA 3.95 (3.72 to 4.19) 2.44 (2.20 to 2.71) 1.62 (1.44 to 1.82)
Seronegative RA 2.47 (2.24 to 2.72) 2.80 (2.34 to 3.35) 0.88 (0.72 to 1.08)
Juvenile idiopathic arthritis 3.98 (3.01 to 5.26) 5.70 (3.47 to 9.36) 0.70 (0.39 to 1.23)
Other inflammation arthritis 1.62 (1.52 to 1.73) 1.54 (1.37 to 1.73) 1.05 (0.92 to 1.20)
Spondyloarthropathies 1.20 (1.16 to 1.25) 1.31 (1.23 to 1.39) 0.92 (0.85 to 0.98)
Psoriasis/psoriatic arthritis 1.23 (1.18 to 1.29) 1.40 (1.29 to 1.51) 0.88 (0.81 to 0.96)
Lupus 1.96 (1.68 to 2.28) 1.80 (1.36 to 2.37) 1.09 (0.79 to 1.49)
Connective tissue diseases 2.04 (1.83 to 2.29) 1.76 (1.43 to 2.17) 1.16 (0.92 to 1.47)
Arthralgia 1.23 (1.18 to 1.28) 1.25 (1.17 to 1.35) 0.98 (0.90 to 1.07)
Osteoarthritis 1.03 (1.00 to 1.06) 1.05 (1.00 to 1.09) 0.98 (0.93 to 1.03)