Table 2.
Baseline Characteristics by Sex in Patients ≤ 55 Years of Age with Acute Myocardial Infarction Undergoing Percutaneous Coronary Intervention
| Patient characteristics | Overall (n=2076) | Women (n=1311) | Men (n=765) | P value |
|---|---|---|---|---|
| Age (years), median (IQR) | 48.0 (44.0 – 52.0) | 49.0 (44.0 – 52.0) | 48.0 (44.0 – 52.0) | 0.13 |
| Obesity (BMI ≥ 30 kg/m2) | 1133 (54.6%) | 764 (58.3%) | 369 (48.2%) | <0.01 |
| Weight (kg), mean (std) | 90.8 (23.1) | 86.7 (22.6) | 97.8 (22.2) | <0.01 |
| Nonwhite race | 469 (22.6%) | 335 (25.6%) | 134 (17.5%) | <0.01 |
| Diabetes mellitus | 720 (34.7%) | 532 (40.6%) | 188 (24.6%) | <0.01 |
| Hypertension | 1368 (65.9%) | 885 (67.5%) | 483 (63.1%) | 0.04 |
| Current smokers | 1194 (57.5%) | 788 (60.1%) | 406 (53.1%) | <0.01 |
| Prior stroke | 84 (4.0%) | 69 (5.3%) | 15 (2.0%) | <0.01 |
| Prior myocardial infarction | 319 (15.4%) | 190 (14.5%) | 129 (16.9%) | 0.15 |
| Prior revascularization | 362 (17.5%) | 211 (16.1%) | 151 (19.9%) | 0.03 |
| Prior heart failure | 68 (3.3%) | 58 (4.4%) | 10 (1.3%) | <0.01 |
| eGFR (ml/min/1.73m2), mean (std) | 89.1 (23.1) | 88.9 (24.7) | 89.4 (20.2) | 0.64 |
| eGFR<50 ml/min/1.73m2 | 98 (4.7%) | 80 (6.1%) | 18 (2.4%) | <0.01 |
| Renal Dysfunction (eGFR<=60) | 211 (10.2%) | 151 (11.6%) | 60 (7.9%) | 0.01 |
| Serum Creatinine (mg/dL), median (IQR) | 0.9 (0.7 – 1.0) | 0.8 (0.7 – 0.9) | 1.0 (0.9 – 1.1) | <0.01 |
| Creatinine >2mg/dL | 45 (2.2%) | 33 (2.5%) | 12 (1.6%) | 0.15 |
| Presentation variables | ||||
| Signs of heart failure | 69 (3.5%) | 51 (4.1%) | 18 (2.5%) | 0.06 |
| Systolic blood pressure (mm Hg), mean (std) | 144.7 (31.0) | 143.5 (32.4) | 146.7 (28.4) | 0.02 |
| Heart rate (bpm), mean (std) | 82.8 (19.6) | 83.6 (19.2) | 81.4 (20.1) | 0.02 |
| ST depression | 855 (41.5%) | 544 (41.8%) | 311 (40.9%) | 0.66 |
| Treatment | ||||
| Aspirin | 2012 (97.3%) | 1263 (96.9%) | 749 (98.2%) | 0.07 |
| Unfractionated heparin | 1623 (78.2%) | 1009 (77.0%) | 614 (80.3%) | 0.08 |
| Glycoprotein IIb/IIIa inhibitors | 1172 (56.5%) | 717 (54.7%) | 455 (59.5%) | 0.03 |
| Eptifibatide | 899 (43.3%) | 556 (42.4%) | 343 (44.8%) | 0.28 |
| Abciximab | 273 (13.2%) | 161 (12.3%) | 112 (14.6%) | 0.12 |
| Clopidogrel | 1718 (89.2%) | 1080 (89.5%) | 638 (88.6%) | 0.55 |
| Prasugrel | 256 (13.3%) | 156 (12.9%) | 100 (13.9%) | 0.55 |
| Ticlopidine | 3 (0.2%) | 2 (0.2%) | 1 (0.1%) | 1.00 |
| Bivalirudin | 692 (33.3%) | 459 (35.0%) | 233 (30.5%) | 0.03 |
*
: All tables percentages are calculated by excluding missing values
Abbreviations: BMI – Body mass index; std – standard deviation; bpm – beats per minute; eGFR – estimated glomerular filtration rate; IQR – interquartile range