Table 1.
No renal disease during follow-up N=19 |
Renal disease at Baseline N=14 |
Renal disease one year or more From Baseline N=14 |
p-value Comparing No renal disease to Renal disease at Baseline |
p-value Comparing Renal disease at Baseline to Renal Disease one year or more from Baseline |
|
---|---|---|---|---|---|
Clinical Characteristics | |||||
Age, years (SD) | 12.9 (3.4) | 11.5 (3.4) | 12.2 (4.4) | 0.2 | 0.6 |
Gender, n (%) F | 19 (100) | 11 (78) | 14 (100) | 0.04 | 0.04 |
Hispanic, n (%) | 0(0) | 1(7) | 1 (7) | 0.7 | 0.4 |
Race, n (%) AA | 14 (74) | 9 (64) | 9 (64) | 0.6 | 0.2 |
Laboratory Parameters | |||||
ANA, n (%) positive | 19 (100) | 14 (100) | 14 (100) | 1 | 1 |
dsDNA, n (%) positive | 13 (68) | 12 (85) | 8 (57) | 0.3 | 0.2 |
Ro, n (%) positive | 5/12 (40) | 2/7 (29) | 2/7 (29) | 0.6 | 1 |
La, n (%) positive | 1/7 (14) | 2/7 (29) | 1/7 (14) | 0.7 | 0.6 |
RNP, n (%) positive | 5/12 (40) | 5/11 (45) | 4/11 (36) | 0.7 | 0.8 |
Sm, n (%) positive | 1/7 (14) | 7/12 (58) | 4/10 (40) | 0.03 | 0.4 |
Low C3, n (%) | 47 | 64 | 64 | 0.3 | 0.9 |
Low C4, n (%) | 56 | 71 | 63 | 0.4 | 0.7 |
Elevated ESR, n (%) | 74 | 57 | 82 | 0.3 | 0.1 |
Low Hgb, n (%) | 16 (84) | 6 (42) | 4 (28) | 0.9 | 0.7 |
Low Albumin, n (%) | 10 (52) | 6 (42) | 3 (21) | 0.9 | 0.4 |
Active Urinary Sediment, n (%) | 0 (0) | 11 (78) | 0 (14) | 0.01 | 0.01 |
Isolated Sterile Pyuria, n (%) | 0 (0) | 0 (14) | 0 (14) | 1 | 1 |
Disease Activity Indices | |||||
Mean SLEDAI | 13.1 ± 9.6 | 10.7 ±11.7 | 12.8 ± 14.2 | 0.6 | 0.4 |
Mean SLAM | 6.1 ± 5.5 | 5.4 ± 3.1 | 5.1 ± 3.6 | 0.8 | 0.6 |