Table 2.

Adjusted^* hazard ratios (95% Confidence Intervals) of incident CHD by 25(OH)D quintile, follow-up: 1990–1992 through December 2011.

	Quintiles of 25(OH)D
	Quintile 1 (<17.0 ng/ml)	Quintile 2–5 (≥17.0 ng/ml)
Overall:
Median 25(OH)D (ng/ml)	13.8	25.9
n events/n at risk	268/2389	962/9556
Model 1	1.30 (1.12–1.51)	1 (reference)
Model 2	1.16 (1.00–1.34)	1 (reference)
Model 3	1.10 (0.94–1.28)	1 (reference)
Model 4	1.11 (0.95–1.29)	1 (reference)
Blacks:
Median 25(OH)D (ng/ml)	13.4	22.0
n events/n at risk	144/1261	217/1653
Model 1	1.06 (0.85–1.32)	1 (reference)
Model 2	1.03 (0.82–1.28)	1 (reference)
Model 3	0.98 (0.78–1.23)	1 (reference)
Model 4	0.98 (0.78–1.24)	1 (reference)
Whites:
Median 25(OH)D (ng/ml)	14.2	26.7
n events/n at risk	124/1128	745/7903
Model 1	1.53 (1.26–1.85)	1 (reference)
Model 2	1.28 (1.05–1.56)	1 (reference)
Model 3	1.21 (0.99–1.47)	1 (reference)
Model 4	1.22 (1.00–1.50)	1 (reference)

^*Model 1: age, sex, race/center (overall model) or center (race-stratified models).

Model 2: +education, physical activity, smoking status, and BMI.

Model 3: +diabetes, systolic blood pressure, diastolic blood pressure, antihypertensive medications, total cholesterol, HDL-C, hsCRP, and eGFR.

Model 4: +calcium, phosphorous, parathyroid hormone, and serum magnesium.