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. 2015 Mar 23;41(4):859–868. doi: 10.1093/schbul/sbv022

Table 2.

Comparison of Changes in Aerobic Fitness, Neurocognition, and Brain-Derived Neurotropic Factor Following Aerobic Exercise or Treatment as Usual

Treatment Intention to Treat (n = 33) Study Completers (n = 26) Cohen’s d b
Mean Δ SD F a P Mean Δ SD F a P
Aerobic fitness Treatment as usual −0.71 2.78 3.62 .001** −0.48 3.07 12.24 .002** 1.06
Aerobic exercise 3.11 3.26 3.82 3.21
Neurocognition Treatment as usual 0.35 7.16 1.34 .19 −1.15 5.80 5.24 .031* 0.93
Aerobic exercise 3.25 4.93 4.00 5.21
BDNF Treatment as usual 1.39 4.64 0.08 .94 0.17 3.50 0.76 .46 0.30
Aerobic exercise 1.26 5.02 1.55 5.56

Note: Aerobic fitness, VO2peak (ml/kg/min); Neurocognition, MATRICS Consensus Cognitive Battery (MCCB) composite score; BDNF, serum BDNF (ng/ml).

aControlling for the impact of sex, age, and changes in antipsychotics, antidepressants and phase of menstrual cycle.

bFor study completers.

*P < .05, **P < .01.

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