Table 6.
Karyotype Diagnostic Yield by CHD Classification
| CHD Class | Karyotypes Performed |
Abnormal Results |
Diagnostic Yield |
p-value |
|---|---|---|---|---|
| Conotruncal | 61 | 1 | 2% | <0.01 |
| LVOTO | 56 | 2 | 4% | 0.06 |
| RVOTO | 16 | 2 | 13% | 0.70 |
| Septal | 9 | 6 | 67% | <0.01 |
| Complex | 8 | 1 | 13% | 0.79 |
| TAPVR | 4 | 0 | 0% | 0.51 |
| Heterotaxy | 2 | 0 | 0% | 0.64 |
| AVSD | 12 | 5 | 42% | <0.01 |
| Other | 6 | 0 | 0% | 0.41 |
| Total | 174 | 17 | 10% |
LVOTO, Left Ventricular Outflow Tract Obstruction; AVSD, Atrioventricular septal defect; RVOTO, Right Ventricular Outflow Tract Obstruction; TAPVR, Total Anomalous Pulmonary Venous Return. Chi-square analyses were performed comparing the karyotype yield of each CHD class with that of the remaining classes.