Table 7.
FISH Diagnostic Yield by CMA classification
| CHD Class | FISH Performed |
Abnormal Results |
Diagnostic Yield |
p-value |
|---|---|---|---|---|
| Conotruncal | 49 | 11 | 22% | <0.01 |
| LVOTO | 39 | 1 | 3% | 0.02 |
| RVOTO | 7 | 0 | 0% | 0.31 |
| Septal | 3 | 2 | 67% | <0.01 |
| Complex | 5 | 0 | 0% | 0.39 |
| TAPVR | 3 | 0 | 0% | 0.51 |
| Heterotaxy | 1 | 0 | 0% | 0.71 |
| AVSD | 6 | 0 | 0% | 0.35 |
| Other | 1 | 0 | 0% | 0.71 |
| Total | 114 | 14 | 12% |
LVOTO, Left Ventricular Outflow Tract Obstruction; AVSD, Atrioventricular septal defect; RVOTO, Right Ventricular Outflow Tract Obstruction; TAPVR, Total Anomalous Pulmonary Venous Return. Chi-square analyses were performed comparing the FISH yield of each CHD class with that of the remaining classes.