Fig. 1. Laser-treated keratinocyte-conditioned medium induced significant increases of inflammatory mediators. Inflammatory mediators including interleukin (IL)-1, IL-8, and prostaglandin E2 (PGE2) were significantly higher in laser-treated keratinocyteconditioned medium (blue) than non-treated keratinocyteconditioned medium (red). Data are mean±standard deviation. ^**p<0.01; Student's t-test.