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. 2015 Jun 12;10(6):e0129853. doi: 10.1371/journal.pone.0129853

Fig 2. Radotinib induces CD11b expression in AML cells.

Fig 2

Cells were incubated with various concentrations of radotinib and/or ATRA for 72 h, harvested and immunostained with an anti-human CD11b mAb. The expression of CD11b was measured by flow cytometry in NB4 (A), HL60 (B), Kasumi-1 (C), and THP-1 cells (D). Data are presented as the mean ± SEM. Statistically significant differences from the DMSO-treated control (*) or ATRA treatment (#) are denoted as follows. **, ##: P < 0.01; ***, ###: P < 0.001. Das, dasatinib; ATRA, all-trans retinoic acid.