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. 2015 Jun 12;10(6):e0129853. doi: 10.1371/journal.pone.0129853

Table 2. Effects of Radotinib on the cell viability in patients with AML and CML.

UPN Disease Cell source 0 μM 1 μM 10 μM 100 μM
1 AML BM 100 ± 0.0 69 ± 1.2 *** 58± 1.5 *** 57 ± 2.3 ***
2 AML BM 100 ± 0.0 75 ± 1.0 *** 73 ± 0.5 *** 68 ± 0.9 ***
3 AML BM 100 ± 0.0 85 ± 2.5 *** 78 ± 2.5 *** 65 ± 2.7 ***
4 AML BM 100 ± 0.0 103 ± 6.5 64 ± 6.2 *** 45 ± 3.5 ***
5 AML BM 100 ± 0.0 95 ± 0.9 ** 90 ± 0.9 *** 78 ± 2.1 ***
6 AML PB 100 ± 0.0 91 ± 3.9 86 ± 6 87 ± 3 *
7 AML PB 100 ± 0.0 94 ± 0.6 ** 90 ± 0.8 ** 69 ± 1.8 ***
8 CML BM 100 ± 0.0 98 ± 7.8 88± 3.7 87 ± 6.3
9 CML BM 100 ± 0.0 91 ± 5.5 95 ± 9.2 77 ± 2.9 **
10 CML BM 100 ± 0.0 96 ± 0.6 100 ± 1 112 ± 2
11 CML BM 100 ± 0.0 99 ± 0.8 102 ± 0.4 113 ± 1
12 CML PB 100 ± 0.0 101 ± 3.2 98 ± 1.4 91 ± 5

These data represent the means ± SEM. Significantly different from control, 0 μM (*);

*: P < 0.05;

**: P < 0.01;

***: P < 0.001.