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. 2015 Jun 12;10(6):e0130207. doi: 10.1371/journal.pone.0130207

Table 5. Risk Factors of the Detection Rate of PCa Analyzed by Cox Proportional Hazard Regression Model.

Variable Unadjusted model Adjusted model
Events, no. HR (95% CI) p value HR (95% CI) p value
Age (per 1 yr) 509/1113 1.04 (1.03–1.05) <0.001 1.01 (1.00–1.02) 0.27
Baseline PSA level (ng/ml)
    0.01–4.00 (13%) 12/132 1 (reference) 1 (reference)
    4.01–10.00 (32%) 102/345 3.59 (1.97–6.53) <0.001 2.54 (1.40–4.63) 0.002
    >10.00 (55%) 388/587 10.81 (6.08–19.22) <0.001 4.42 (2.46–7.94) <0.001
Score of PI-RADS
    1–2 (49%) 44/541 1 (reference) 1 (reference)
    3 (10%) 53/109 7.24 (4.85–10.80) <0.001 6.43 (4.29–9.65) <0.001
    4–5 (41%) 412/463 25.09 (18.23–34.54) <0.001 18.58 (13.36–25.84) <0.001

PCa: prostate cancer; HR: hazard ratio; CI: confidence interval; PSA: prostate specific antigen; PI-RADS: Prostate Imaging Reporting and Data System.