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. 2015 Jun 12;10(6):e0129124. doi: 10.1371/journal.pone.0129124

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© 2015 Smorodinova et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 2 — A-D: Immunohistochemical reaction shows collagen III in endomysial and partly also perimysial extracellular matrix. In atria of both patient groups (SR in A, B and AF in C, D) it is possible to detect higher (A, C) as well as lower (B, D) amount of collagen III-positive ECM. Immunoperoxidase reaction with DAB as a substrate (brown precipitate). No nuclear counterstaining. For all images scale bar = 50μm. (E) A graph showing the result of quantification of collagen III volume fraction (CIIIVF) in atrial myocardial samples. A comparison between different anatomical locations is shown: right appendage–RA (n = 37), left appendage–LA (n = 19), left atrium—LAt (n = 9), LA+LAt (n = 28).