Skip to main content
. 2015 Jun 12;10(6):e0129325. doi: 10.1371/journal.pone.0129325

Fig 6. Examples of false negatives, or lesions missed by either of the reviewers.

Fig 6

A. While both reviewers identified various lobar brain regions of reduced diffusivity affected by hypoglycemia in this 9-day old male infant, right hippocampal involvement was noted on Echo2 and cEcho2 (not shown) but not for Echo1 or cEcho1. In retrospect, subtle high signal in right hippocampus on Echo1 (arrow) is identified but less conspicuous compared to Echo2. B. Same patient as Fig 5B where focal lesion in right cerebral peduncle was overlooked by both reviewers, perhaps due to small size, but identified by Reviewer1 on both Echo2 (arrow) and cEcho2 (not shown). C. Focal lesion in the left pons was identified by both reviewers on cEcho2 (arrow) and Echo2 (not shown) and but missed on Echo1 and cEcho1 in this 9-week old infant with cardiac arrest. D. Focal embolic infarct in the left caudate of a 63-week old female infant was missed on Echo1 by both reviewers but detected on cEcho2 (arrow), as well as Echo2 (not shown) and cEcho1.