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Fundus of an RP patient at different stages. (a) Image of a normal healthy eye. (b) Fundus of an RP patient at early stage. (c) Midstage of the disease showing midperipheral pigment deposits. (d) End-stage fundus showing pigment deposit present all over retina with thin retinal vessels and pale optic disc, modified from Hamel [23]. (e-f) End-stage fundus of an RP patient with an RPGR mutation c.852c>G (p.S284X), modified from Yang et al., 2014 [73].
