Table 3. Cytokines, blood counts and biochemistry after short and endurance exercise as compared with baseline.
| Baseline | Post-race | p-value | |
|---|---|---|---|
| Measures of Cardiac Dysfunction | |||
| cTnI (μg/L) | 0.010 ± 0.03 | 0.14 ± 0.17 | <0.0001 |
| cTnI > 0.04 μg/L (n, %) | 0 | 31, 78% | <0.0001 |
| BNP (ng/L) | 13.2 ±14.2 | 25.4 ± 21 | 0.002 |
| ΔBNP > 10 ng/L (n, %) | - | 19, 48% | |
| RVEF (%) | 51.0 ± 3.6 | 46.4 ± 6.5 | <0.0001 |
| ΔRVEF > -10.6% (n, %) | - | 18, 45% | |
| ‘Myocardial dysfunction’ (n, %) | 0 | 10, 25% | 0.0007 |
| Inflammatory cytokines | |||
| IL-6 (pg/ml) | 3.91 ± 3.81 | 33.35 ± 24.01 | <0.0001 |
| IL-8 (pg/ml) | 6.90 ± 5.41 | 19.81 ± 10.62 | <0.0001 |
| IL-10 (pg/ml) | 2.85 ± 3.20 | 20.18 ± 22.52 | <0.0001 |
| IL-1β (pg/ml) | 3.62 ± 3.39 | 3.95 ± 3.82 | 0.444 |
| IL-12p70 (pg/ml) | 3.81 ± 4.00 | 3.81 ± 3.69 | 0.829 |
| TNFα (pg/ml) | 2.73 ± 3.80 | 3.39 ± 3.85 | 0.161 |
| Hematology | |||
| Hb (g/l) | 138.6 ± 7.6 | 149.1 ± 8.4 | <0.0001 |
| Haematocrit (%) | 40.6 ± 2.4 | 44.1 ± 2.5 | <0.0001 |
| WCC (x109/l) | 5.81 ± 1.43 | 15.17 ± 3.84 | <0.0001 |
| Platelets (x109/l) | 250.5 ± 43.9 | 308.4 ± 55.5 | <0.0001 |
| Biochemistry | |||
| Na (mmol/l) | 138.4 ± 1.9 | 140.9 ± 2.9 | 0.002 |
| K (mmol/l) | 4.22 ± 0.24 | 4.93 ± 0.88 | 0.001 |
| Creatinine (μmol/l) | 79.9 ± 7.6 | 111.3 ± 19.2 | <0.0001 |
| CK (U/L) | 305 ± 208 | 1001± 1006 | <0.0001 |
| Osmolality (mmol/kg) | 285.8 ± 5.0 | 291.6 ± 7.4 | 0.002 |