Table 4. Metabolic syndrome and fracture risk.
| Women | Men | ||||
|---|---|---|---|---|---|
| All Fractures (371) | All Fractures (147) | ||||
| Metabolic Syndrome | Hazard ratio (95%CI) | P-value | Metabolic Syndrome | Hazard ratio (95%CI) | P-value |
| Model 1 | 0.85 (0.69–1.04) | 0.12 | Model 1 | 0.85 (0.60–1.20) | 0.36 |
| Model 2 | 0.91 (0.72–1.14) | 0.40 | Model 2 | 0.74 (0.69–1.08) | 0.12 |
| Model 3 | 0.91 (0.73–1.15) | 0.43 | Model 3 | 0.68 (0.46–1.006) | 0.054 |
| No. of MS components | No. of MS components | ||||
| Model 1 | 0.94 (0.87–1.02) | 0.11 | Model 1 | 0.92 (0.81–1.06) | 0.24 |
| Model 2 | 0.97 (0.89–1.05) | 0.44 | Model 2 | 0.86 (0.74–1.001) | 0.055 |
| Model 3 | 0.97 (0.89–1.06) | 0.47 | Model 3 | 0.82 (0.70–0.9964) | 0.015 |
| Non-Vertebral Fractures (307) | Non-Vertebral Fractures (102) | ||||
| Metabolic Syndrome | Hazard ratio (95%CI) | P-value | Metabolic Syndrome | Hazard ratio (95%CI) | P-value |
| Model 1 | 0.90 (0.72–1.13) | 0.36 | Model 1 | 0.89 (0.59–1.35) | 0.59 |
| Model 2 | 0.94 (0.73–1.21) | 0.63 | Model 2 | 0.69 (0.55–1.88) | 0.12 |
| Model 3 | 0.94 (0.73–1.21) | 0.61 | Model 3 | 0.64 (0.40–1.03) | 0.068 |
| No. of MS components | No. of MS components | ||||
| Model 1 | 0.96 (0.89–1.05) | 0.38 | Model 1 | 0.94 (0.79–1.10) | 0.42 |
| Model 2 | 0.98 (0.89–1.08) | 0.70 | Model 2 | 0.83 (0.68–1.01) | 0.047 |
| Model 3 | 0.98 (0.89–1.08) | 0.66 | Model 3 | 0.75 (0.66–0.96) | 0.017 |
| Vertebral Fractures (123) | Vertebral Fractures (62) | ||||
| Metabolic Syndrome | Hazard ratio (95%CI) | P-value | Metabolic Syndrome | Hazard ratio (95%CI) | P-value |
| Model 1 | 0.68 (0.47–0.98) | 0.039 | Model 1 | 0.65 (0.37–1.13) | 0.13 |
| Model 2 | 0.80 (0.53–1.19) | 0.27 | Model 2 | 0.67 (0.49–1.25) | 0.20 |
| Model 3 | 0.83 (0.56–1.24) | 0.36 | Model 3 | 0.60 (0.32–1.14) | 0.12 |
| No. of MS components | No. of MS components | ||||
| Model 1 | 0.84 (0.73–0.96) | 0.01 | Model 1 | 0.84 (0.6–1.03) | 0.10 |
| Model 2 | 0.86 (0.76–1.03) | 0.11 | Model 2 | 0.85 (0.75–1.07) | 0.17 |
| Model 3 | 0.90 (0.77–1.05) | 0.18 | Model 3 | 0.81 (0.64–1.03) | 0.09 |
“( )”, number of fractures
Model 1: Adjusted for age
Model 2: Model 1 +Height and Weight
Model 3: Model 2 + smoking status, physical activity, alcohol intake, fallings in the last 12 months, use of diuretics drugs, use of hormone replacement therapy, use of corticosteroids drugs, use of drugs for bone and other musculoskeletal diseases and Dutch Healthy Diet Index.