Skip to main content
. 2015 Feb 4;6(9):7011–7022. doi: 10.18632/oncotarget.3137

Figure 2. Depletion of TNKS1BP1 leads to defective DNA double-strand break repair.

Figure 2

(A) Immunofluorescence staining image of γH2AX foci in TNKS1BP1 depleted HeLa-shTNKS1BP1 cells and control HeLa-NC cells at given times after 4 Gy of γ-rays. (B) Residual number of γH2AX foci per cell after certain times of repair in 4 Gy irradiated cells. **P < 0.01. (C) Pulsed-gel electrophoresis (PFGE) pattern of DNA double-strand breaks and repair in 4 Gy-irradiated cells. (D) Repair kinetics of 4 Gy-induced DSBs detected by PFGE. *P < 0.05.