Skip to main content
. 2015 May 26;112(23):7237–7242. doi: 10.1073/pnas.1505924112

Fig. 1.

Fig. 1.

The pH-dependent conformational change of DEC205. (A) A schematic representation of DEC205 domain arrangement. (B) SEC profiles of DEC205 at pH 6 and pH 8. (C) Dynamic light scattering analysis of DEC205 at pH 6 and pH 8. (D) A negatively stained EM micrograph (Top) and the representative reference-free 2D classes (Bottom) of DEC205 at basic pH. (E) A negatively stained EM micrograph (Top) and the representative reference-free 2D classes (Bottom) of DEC205 at acidic pH. (F) A cryoEM micrograph (Top) and the representative reference-free 2D classes (Bottom) of DEC205 at acidic pH. (Scale bars, 50 nm for micrographs and 10 nm for the reference-free 2D classes.)