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. 2015 May 28;112(23):E3010–E3019. doi: 10.1073/pnas.1505870112

Fig. 3.

Fig. 3.

Prdm8-null mice have a nonprogressive defect in retinal responses postsynaptic to PRs. ERG responses of 3- and 6-mo-old WT and Prdm8EGFP/EGFP mice. (A and D) The rod-driven b-wave response was clearly attenuated in Prdm8EGFP/EGFP mice at 3 mo of age compared with the WT and remained attenuated at 6 mo of age. (B and E) The standard combined b-wave response of Prdm8EGFP/EGFP mice at 3 and 6 mo was reduced compared with WT, whereas the a wave was normal. (C and F) Cone-derived ERG responses at 3 and 6 mo also showed a reduction in the b wave but not the a wave in Prdm8EGFP/EGFP mice compared with the WT.