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. 2015 Jun 16;15:19. doi: 10.1186/s12880-015-0062-3

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© Barnes et al. 2015

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — K_trans fitting of simulated data. Simulated data with time resolution of 0.5 s and SNR = 100 were fitted using the same model used to generate the simulation with ROCKETSHIP using default settings for the Patlak method (a), Tofts (b) and Extended Tofts models (c). K_trans simulated vs. fitted were plotted as a function of v_e and v_p. Dashed line is unity. Error bars denote standard deviation. Given the similar fits, points for different v_e and v_p may overlap. Concordance correlation coefficients for these (and other model fits) are shown in Tables 3, 4 and 5