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. 2015 Jun 16;15:19. doi: 10.1186/s12880-015-0062-3

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© Barnes et al. 2015

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — v_e fitting at different time resolutions. Simulated data using the Tofts model were generated at SNR = 5 and at time resolutions of 0.5 s (a) and 6 s (b). Simulated vs. fitted v_e were plotted as a function of K_trans. Dashed line is unity. Error bars represent standard deviation. As expected, lower time resolution results in a high standard deviation of the curve fits. Given the similar fits, points for different K_trans may overlap. Concordance correlation coefficients for these (and other model fits) are shown in Tables 3, 4 and 5