Table 4.
Bone metabolism-related biochemical markers in serum
| Sham | STZ | US | |
|---|---|---|---|
| Intact PTH (pg/mL) | 109 ± 5.1 | 164 ± 8.7* | 125 ± 4.2# |
| FGF-23 (pg/mL) | 385 ± 20.7 | 188 ± 16.3* | 301 ± 17.4# |
| TRACP-5b (pg/mL) | 2.75 ± 0.37 | 2.87 ± 0.49 | 2.79 ± 0.31 |
| OCN (ng/mL) | 556 ± 25.8 | 339 ± 29.9* | 476 ± 29.1# |
| CTX (ng/mL) | 37 ± 4.4 | 69 ± 5.9* | 48 ± 6.2# |
| TES (ng/mL) | 3.6 ± 0.53 | 1.2 ± 0.44* | 1.8 ± 0.45 |
| b-ALP (ng/mL) | 2.33 ± 0.05 | 1.65 ± 0.06* | 2.18 ± 0.05# |
Values are expressed as mean ± SEM, n = 6 in each group.
*
P < 0.05, versus vehicle;
#
P < 0.05, versus STZ.
PTH, parathyroid hormone; FGF-23, fibroblast growth factor-23; TRACP-5b, tartrate resistant acid phosphatase-5b; OCN, osteocalcin; CTX, C-terminal telopeptide of type I collagen; TES, testosterone; b-ALP, bone specific alkaline phosphatase.