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. 2015 Apr 1;8(4):3864–3870.

Figure 3.

Figure 3

IGF1R was a target of miR-139-5p in NSCLC cells. A. A schematic illustration of Wt and Mut 3’-UTR of IGF1R. B. Luciferase activity assay shown that miR-139-5p suppressed Wt IGF1R 3’-UTR luciferase activity, while it had no effect on Mut IGF1R 3’-UTR luciferase activity compared to control in A549 cells. C. Expression of IGF1R was detected by Western blot in A549 cells transfected with miR-139-5p mimics or miR-NC. β-actin was used as a control. Data are presented as means ± SD from three independent experiments. *P<0.05.