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Decreased expression of IGF1R showed similar effect with miR-139-5p over-expression. (A) Knockdown of IGF1R by siRNA (si-IGF1R) was confirmed by qRT-PCR in A549 cells. (B) The vitality of A549 cells transfected with si-IGF1R or si-NC was detected using the MTT assay. (C, D) Transwell assays were used to detect migration (C) and invasion (D) of A549 cells transfected with si-IGF1R or si-NC. Data are presented as means ± SD from three independent experiments. *P<0.05.
