Table 3.
Association of SOX9 expression levels with therapeutic response to sorafenib/sunitinib
| SOX9 (+) (%) | SOX9 (-) (%) | P Value | |
|---|---|---|---|
| CR | 0/16 (0%) | 1/22 (4.5%) | 0.453 |
| PR | 3/16 (18.8%) | 9/22 (40.9%) | 0.354 |
| SD | 4/16 (25%) | 10/22 (45.5%) | 0.197 |
| PD | 9/16 (56.2%) | 2/22 (9.1%) | 0.002 |
| ORR | 3/16 (18.8%) | 10/22 (45.4%) | 0.087 |
| DCR | 7/12 (43.8%) | 20/22 (90.9%) | 0.002 |
Therapeutic response was evaluated according to RECIST criteria. CR: Complete Response, PR: Partial Response, SD: Stable Disease, PD: Progressive Disease, ORR: Objective Response Rate, DCR: Disease Control Rate.