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. 2015 Feb 3;17(1):21. doi: 10.1186/s13075-015-0533-5

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© Kelley et al. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Forest plot for changes in depressive symptoms. Forest plot for point estimate changes in depressive symptoms. The black squares represent the mean difference while the left and right extremes of the squares represent the corresponding 95% confidence intervals. The middle of the black diamond represents the overall mean difference while the left and right extremes of the diamond represent the corresponding 95% confidence intervals. Combined measures represent those studies in which multiple assessment instruments for depression and/or per-protocol and intention-to-treat analyses were merged.