Use	Application(s)/Product(s)	Company	Approval Year	Nanocomponent Description
Bone Substitute	Vitoss [14]	Orthovita	2003	100 nm Calcium-Phosphate Nanocrystals
	Ostim [87]	Osartis	2004	20 nm Hydroxapatite Nanocrystals
	OsSatura [62]	Isotis Orthobiologics US	2003	Hydroxapatite Nanocrystals
	NanOss [77]	Angstrom Medica, Inc.	2005	Hydroxapatite Nanocrystals
	Alpha-bsm, Beta-bsm, Gamma-bsm, EquivaBone, CarriGen [93]	ETEX Corporation	2009	Hydroxapatite Nanocrystals
Dental Composite	Ceram × Duo [94]	Dentspley	2005	Ceramic Nanoparticles
	Filtek [95]	3M Company	2008	Silica and Zirconium Nanoparticles
	Premise [14]	Sybron Dental Specialties	2003	"Nanoparticles"
	Nano-Bond [96]	Pentron® Clinical Technologies, LLC	2007	"Nanoparticles"
Device Coating	ON-Q SilverSoaker / SilvaGard™ [97]	I-Flow Corporation / AcryMed, Inc.	2005	Anti-Microbial Nanosilver
	EnSeal Laparoscopic Vessel Fusion [39]	Ethicon Endo-Surgery, Inc.	2005	Nanoparticle Coated Electrode
	NanoTite Implant [98]	Biomet	2008	Calcium Phosphate Nanocrystal Coating
In Vitro Assay	CellTracks® [14]	Immunicon Corporation	2003	Magnetic Nanoparticles
	NicAlert [14]	Nymox	2002	Colloidal Gold
	Stratus CS [62]	Dade Behring	2003	Dendrimers
	CellSearch® Epithelial Cell Kit [99]	Veridex, LLC (Johnson & Johnson)	2004	Iron-Oxide Nanoparticles
	Verigene [100,101]	Nanosphere, Inc.	2007	Colloidal Gold
	MyCare™ Assays [102]	Saladax Biomedical	2008	"Nanoparticles"
Medical Dressing	Acticoat® [97,103]	Smith & Nephew, Inc.	2005	Anit-Microbial Nanosilver
Dialysis Filter	Fresenius Polysulfone® Helixone® [104]	NephroCare	1998	Nanoporous Membrane
Tissue Scaffold	TiMESH [39]	GfE Medizintechnik GmbH	2004	30 nm Titanium Coating