Table 1. The relationship between expression of CXCR4/CXCL12 and clinicopathological features in 78 cases of PCa.
| CXCR4 n (%) | CXCL12 n (%) | ||||||
|---|---|---|---|---|---|---|---|
| All Cases | Negative n=16 (20.5%) | Positive n=62 (79.5%) | P Value∆ | Negative n=24 (20.5%) | Positive n=54 (79.5%) | P Value∆ | |
| Sex | 0.626 | 0.698 | |||||
| Male | 48 | 9 (18.8) | 39 (81.2) | 14 (29.2) | 34 (70.8) | ||
| Female | 30 | 7 (23.3) | 23 (76.7) | 10 (33.3) | 20 (66.7) | ||
| Age (Years) | 0.146 | 0.241 | |||||
| ≤57† | 41 | 11 (26.8) | 30 (73.2) | 15 (36.6) | 26 (63.4) | ||
| >57 | 37 | 5 (13.5) | 32 (86.5) | 9 (24.3) | 28 (75.7) | ||
| Histological grade | 0.691 | 0.196 | |||||
| Well | 23 | 5 (21.7) | 18 (78.3) | 6 (26.1) | 17 (73.9) | ||
| Moderate | 36 | 6 (16.7) | 30 (83.3) | 9 (25.0) | 27 (75.0) | ||
| Poor | 19 | 5 (26.3) | 14 (73.7) | 9 (47.4) | 10 (52.6) | ||
| Lymph node metastasis | 0.045* | 0.639 | |||||
| Negative | 49 | 14 (28.6) | 35 (71.4) | 16 (32.7) | 33 (67.3) | ||
| Positive | 29 | 2 (6.9) | 27 (93.1) | 8 (27.6) | 21 (72.4) | ||
| TNM stage (AJCC) | 0.037* | 0.868 | |||||
| I | 23 | 9 (39.1) | 14 (60.9) | 8 (34.8) | 15 (65.2) | ||
| II | 35 | 6 (17.1) | 29 (82.9) | 10 (28.6) | 25 (71.4) | ||
| III | 9 | 1 (11.1) | 8 (88.9) | 2 (22.2) | 7 (77.8) | ||
| IV | 11 | 0 (0) | 11 (100.0) | 4 (36.4) | 7 (63.6) | ||
| Vascular invasion | 0.049* | 0.819 | |||||
| Negative | 44 | 13 (29.5) | 31 (70.5) | 14 (31.8) | 30 (68.2) | ||
| Positive | 34 | 3 (9.8) | 31 (91.2) | 10 (29.4) | 24 (70.6) | ||
| Perineural invasion | 0.0001* | 0.225 | |||||
| Negative | 25 | 12 (48.0) | 13 (52.0) | 10 (40.0) | 15 (60.0) | ||
| Positive | 53 | 4 (7.5) | 49 (92.5) | 14 (26.4) | 39 (73.6) | ||
∆
χ2 test;
*
Significant different, P<0.05;
†
Mean age