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. 2014 Dec 3;6(7):4745–4756. doi: 10.18632/oncotarget.2938

Table 1. Mutational gene profile of human CRC cells.

Cell Line KRAS BRAF PI3KCA TP53
HCT116(p53+/+) G13D WT H1047R WT
HCT116(p53−/−) GI3D WT H1047R KO
RKO WT V600E H1047R WT
HT29 WT V600E P449T R273H
SW48 WT WT WT WT
SW48− WT WT WT R273H
TP53(R273 H/+)

The gene mutation status was obtained from the COSMIC website (http://cancer.sanger.ac.Uk/cancergenome/projects/cosmic/).

WT: wild type; KO: gene knockout.