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. 2014 Dec 31;6(7):4936–4952. doi: 10.18632/oncotarget.3210

Table 1. Tumorigenic potential of shLuc- or shGal-3-infected monolayers or spheres from H1299 cell line.

No. of injected cells No. of mice with tumor formation/Total No. of mice with cell injection
Monolayers
H1299/shLuc 1 × 104 0/4
1 × 105 1/4
1 × 106 4/4
H1299/shGal-3 1 × 104 0/4
1 × 105 0/4
1 × 106 2/4
Spheres
H1299/shLuc 1 × 104 3/4
1 × 105 4/4
1 × 106 4/4
H1299/shGal-3 1 × 104 0/4
1 × 105 1/4
1 × 106 3/4

Notes: lentiviral shRNA infected cells were dissociated and subcutaneously injected in NOD/SCID mice (n = 4 per group). The tumor formation was detected 10 weeks after injection.