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. 2014 Dec 31;6(7):4953–4967. doi: 10.18632/oncotarget.3211

Figure 4. hMSCs derived EVs are internalize by cancer cells and support cell survival.

Figure 4

(A) MCF-7 breast cancer cells and KHOS osteosarcoma cells incubated with PKH26 labeled SD-MSCs derived EVs for 3 h. EVs have been internalized by cancer cells. Bar represents 100 μm. Insets shows the magnified image. (B) MCF-7 and (C) KHOS cells were cultured in either serum containing media or serum deprived media or serum deprived media supplemented with EVs. The cell survival is quantified by Cyquant DNA quantification method (*P < 0.05; **P<0.018; n=3).