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. 2014 Dec 31;6(7):5022–5040. doi: 10.18632/oncotarget.3217

Figure 10. Forest plots show association between CXCR4 over-expression and overall survival (OS) in hematological malignancy.

Figure 10

(A) Summary for all seven trials, the estimates is 1.18(1.11-1.26) using fixed effects model. (B) Excluding the only study focused on myelodysplastic syndrome (Zhang, 2012) yield results without significant heterogeneity. The estimate is 2.19(1.68-2.85) using fixed effects model. (C) Funnel plots showing association of CXCR4 and OS in hematological malignancy. Visual inspection of the Begg funnel plot did not identify substantial asymmetry.