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. 2014 Dec 31;6(7):5022–5040. doi: 10.18632/oncotarget.3217

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Copyright: © 2015 Zhao et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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(A) Summary for all five trials, the estimates is 1.33(0.94-1.87) using fixed effects model. (B) Although two studies appeared to be outliers (Koishi, 2006; Sasaki, 2009), we did not find clinical heterogeneity justifying their exclusion. Excluding two studies yield results without significant heterogeneity. The estimate is 1.88(0.95-3.70) using fixed effects model. (C) Funnel plots showing association of CXCR4 and OS in gastric cancer. Visual inspection of the Begg funnel plot did not identify substantial asymmetry.