Figure 1. An unbiased MYCN 3′UTR-miRNA library screen identifies 29 miRNAs potentially targeting MYCN.
(A) Average interaction scores are plotted (Y-axis) for 470 tested miRNAs (X-axis). The 29 miRNAs with an interactions core of < −1.94 are listed in Fig. 2A. The 11 interactions that have been reported in literature, are indicated in black. (B) Cumulative distributions (Y-axis) of the interaction scores (X-axis) of miRNAs that respectively have 6-, 7- or 8-mer seed-matches in the MYCN 3′UTR.