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. Author manuscript; available in PMC: 2015 Jun 15.
Published in final edited form as: Annu Rev Biomed Eng. 2014 May 29;16:371–396. doi: 10.1146/annurev-bioeng-121813-120704

Figure 6.

Figure 6

Highlighted applications of inertial focusing. (a) Sheathless alignment of cells in asymmetric curves for enhanced separation efficiency in magnetophoresis (96), showing cells (i) prior to focusing, (ii) after focusing, (iii) during magnetophoresis, and (iv) after complete separation. (b) Isolation of CTCs from blood cells by size in a spiral device. (Panel reprinted by permission from Macmillan Publishers Ltd: Scientific Reports from 103, copyright 2013.) (c) Bacteria filtration from blood using a straight inertial focusing channel (97). (Panel reprinted with permission; copyright 2010 Wiley Periodicals, Inc.) (d) Extraction of plasma from diluted blood in a spiral device. (Panel reprinted with permission from 106; copyright 2013, AIP Publishing LLC.) (e) Volume reduction of a sample of bioparticles using a spiral inertial focusing device. (Panel reprinted with permission from 57; copyright 2013, AIP Publishing LLC.) (f) Solution exchange in which a bead moves from one fluid to another in a straight channel of changing aspect ratio (110). (Panel reprinted with permission; copyright 2012, Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.) Abbreviations: CTC, circulating tumor cell; De, Dean number.